One of our top priorities at Partners is to address the gap in Innovation between discovery and clinical proof-of-concept, where many promising technologies are stranded. This is often called the valley of death, where it is estimated that for every 5,000-10,000 compounds that enter the drug discovery pipeline, only 250 will progress to pre-clinical development.  


Partners Innovation is 'bridging the gap' with growth opportunities for early-stage ventures within the Partners Network that provides patients with greater access to potentially life-saving and life-improving technologies. 


With the addition of TIF and AIDF to our already established Partners Innovation Fund, we address unmet clinical needs by increasing our translational, pre-clinical, and pre-commercial development capabilities.  This encourages more early-stage and pre-clinical development throughout the Partners investigator community, and in the long-term, improves the lives of our patients.

About the Translational Innovation Fund (TIF)


The Translational Innovation Fund (TIF) provides resources to advance promising therapeutics through pre-clinical translation, focusing on discoveries from the Partners' hospitals.


TIF shares in PIF's overall mission to serve unmet medical needs by bringing to market new drugs and medical technologies based on scientific breakthroughs originating at Partners. With funding of $50M over six years,TIF addresses assets not yet ready for venture, and will conduct the development work to accelerate the technology's transition to VC-ready status.  


About the Artificial Intelligence and Digital Translation Fund (AIDIF)


Partners’ Artificial Intelligence and Digital Translation Fund (AIDIF) invests in Digital Solutions, creating opportunities within a 'real-time lab' approach.   


Digital solutions from more than 4,000 new company entrants into the marketplace require active testing, adaptation, and roll-out across actual clinical environments before widespread use. Such specialized co-development relies on health systems such as Partners HealthCare.  With initial funding of $30M over five years, AIDIF helps perfect these products and define how to integrate applications into clinical workflows and create reference models for other health systems. 

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